Case Study Health Decision Technologies · 2013–2021

CAREiSCOPE:
Turning access
into outcomes

A HIPAA-compliant mobile care platform for underserved populations — translating NIH-funded research into real-world clinical outcomes by solving for access, engagement, and behavior simultaneously.

Role
Product Lead / Founder, HDT
Partners
UVA School of Medicine · NIH/NIDA · M·A·C AIDS Fund · Virginia Department of Health
Population
People Living with HIV (PLWH)
CAREiSCOPE app on mobile device
+119%
Retention in care (visit constancy, 12-month)
+64%
Viral suppression (baseline → 12 months)
−83%
ED visits (LifeLong FQHC pilot)
327%
ROI in 6-month P4P pilot

A care gap that existing tools couldn't close

Despite nearly all people living with HIV being aware of their diagnosis, the U.S. HIV care continuum revealed a persistent, systemic breakdown: the further patients moved along the continuum toward viral suppression, the steeper the drop-off.

The gap wasn't awareness — it was sustained engagement. Patients were falling out of care due to geography, poverty, stigma, distrust, and the practical impossibility of showing up at a clinic when life is unstable.

~500,000
Americans living with HIV who were diagnosed but not virally suppressed — accounting for 61% of new transmissions and $8.9B annually in avoidable costs

Existing tools — SMS texting, patient portals, phone calls — were insufficient. They were one-directional, literacy-dependent, or simply not used. A new model was needed: one designed for the realities of this population, not the ideals of a clinical trial.

HIV Care Continuum data: National HIV/AIDS Strategy. PLWH transmission data: Skarbinski et al., JAMA Internal Medicine, 2015.
01 / Access
Geography & Transportation
The clinic's patient population was dispersed across 45,000 sq. miles with average travel times of 2+ hours to the facility. Missing one appointment could cascade into lost care status.
02 / Engagement
One-way, Low-bandwidth Tools
Patient portals had sub-25% usage. SMS texting was blunt and ineffective for sustained behavior change. Neither created the "warm" contact needed to maintain care relationships.
03 / Equity
Digital Divide as a Social Determinant
72% of target patients were below the federal poverty line. Access to mobile data wasn't a feature consideration — it was a precondition that most tools simply ignored.
04 / Stigma
Disclosure Risk & Social Isolation
HIV stigma is a documented driver of disengagement from care. Any platform solution had to enable community and connection without exposing users to disclosure risk.

Prevalence-based HIV Care Continuum

U.S. and 6 Dependent Areas, 2019

Percent of all people living with HIV

Diagnosed 87%, Receipt of Care 66%, Retained in Care 50%, Viral Suppression 57%.

Note: Receipt of care = ≥1 test (CD4 or VL) in 2019. Retained in care = ≥2 tests ≥3 months apart. Viral suppression = <200 copies/mL on most recent test.

Retained in Care
50%

of persons with diagnosed HIV infection remain retained in ongoing care — the critical gap CAREiSCOPE was designed to close.

The problem wasn't awareness — 87% of PLWH knew their diagnosis. The gap was sustained engagement with care after diagnosis.

Built from evidence — not assumptions

CAREiSCOPE grew from a decade of NIH-funded mHealth research at the University of Virginia's Infectious Disease Clinic (Ryan White Part C, 750 PLWH). I joined as product lead in partnership with Dr. Rebecca Dillingham and Dr. Karen Ingersoll, translating their formative research into a deployable clinical product.

The PositiveLinks research program — two formative pilots from 2013–2017 — provided the evidentiary foundation. Targeted at patients most at risk: newly diagnosed, history of missed visits, below the federal poverty line. Medically complex, multiple comorbidities, 67% with behavioral health diagnoses.

This wasn't a consumer app looking for a clinical use case. It was a clinical system built from the ground up to answer one question: what does it actually take to keep the highest-risk patients in care?

PositiveLinks Pilot outcomes published in AIDS Patient Care and STDs (2018) and AIDS and Behavior (2017, 2018). Funded through NIH/NIDA.
i

Two Formative Pilots

Both pilots targeted highest-risk patients. Pilot outcomes published across four peer-reviewed papers

ii

Academic Medical Center Partnership

Co-developed with UVA School of Medicine faculty including Dr. Dillingham (ID), Dr. Ingersoll (Psychiatry), and Dr. Flickinger (General Medicine) — each contributing domain expertise to the behavioral and clinical design.

iii

Real-World Deployment Philosophy

From day one, the design principle was that the platform had to work for the most marginalised patients — not the median patient. That constraint produced a more robust, more equitable product.

A complete system — not a feature set

CAREiSCOPE was designed as a three-layer system: a patient-facing iOS/Android app, a HIPAA-compliant cloud infrastructure, and a web-based clinical administrative portal. Every component was purpose-built to work in concert — not assembled from off-the-shelf tools.

The design philosophy was rooted in three principles borrowed directly from the research: language should not be a barrier, location should not be a barrier to care, and literacy should not be a barrier.

This meant real-time translation to 100+ languages, telemedicine-capable video visits, HIPAA-compliant document handling, and an interface designed for low digital literacy — all without sacrificing security or clinical utility.

CAREiSCOPE Incentive Loop diagram
Member App
Patient-Facing Mobile Experience
iOS and Android app with daily mood and stress monitoring, personalized medication reminders, appointment tracking, labs monitoring, and a private peer support community. Invitation-only, clinic-centered, and designed for security, privacy, and low-literacy contexts.
Virtual Peer Support
Anonymous Social Network for Health
A private, clinic-localized community using anonymous avatars and nicknames — a Twitter-like social layer that enabled peer connection without disclosure risk. Analysis showed 52% of posts were providing support, 14% seeking it, and 35% general community engagement.
Admin Portal
Clinical Back-End & Remote Monitoring
Web-based dashboard for case managers with member dashboards, secure messaging, remote patient monitoring, predictive alerting, video visits, appointment coordination, and API integration with EMR and HIT systems. Dynamic reporting and content management tools included.
Dynamic Translation
Real-Time Multilingual Support
On-the-fly localization to 100+ languages including Spanish, Hmong, Hindi, Japanese, and Chinese. Bi-directional translation in both the member app and admin portal, enabling case managers to serve multilingual patient populations without requiring multilingual staff.
Digital Paperwork
HIPAA-Compliant Document Handling
Secure mobile document transmission and storage for eligibility verification, program enrollment, re-certification, and document checks — removing administrative barriers that routinely caused patients to lose care status due to paperwork, not clinical need.
Assessments
Validated Instruments, Deployed at Scale
Built-in validated instruments including PHQ-9 Depression, self-efficacy, stigma, and substance use scales. Weekly "quiz" capability for single-issue queries. All deployable on-the-fly by clinical administrators without engineering support.

Converting a social determinant into an engagement driver

CAREiSCOPE Incentive Loop — Engage, Earn, Access, Improve

The most consequential design decision in CAREiSCOPE wasn't a feature — it was a behavioral economics model that reframed the problem of mobile data access as a reinforcing incentive loop.

For 72% of CAREiSCOPE's target population, access to mobile data was not guaranteed. Standard digital health products treat this as a deployment limitation. We treated it as a design constraint to solve.

01

Engage & Participate

Patients complete daily check-ins, medication queries, and community interactions — generating engagement data for the clinical team.

02

Earn Data Credits

Engagement is rewarded through the optional RealHealthRewards program: $50/month in mobile data reimbursement when response rate exceeds 50%.

03

Access & Use

Mobile data access enables patients to reach health resources, messaging, appointment coordination, and peer support — between clinic visits.

04

Improve Adherence & Outcomes

Sustained engagement drives viral suppression, retention in care, and reduced avoidable utilization — reinforcing the loop with measurable health benefit.

The key insight: mobile data wasn't just a distribution channel — it was a social determinant we could directly address. By making health engagement the mechanism for data access, we created a self-reinforcing loop in which the act of staying in care funded the ability to stay in care.

Measurable impact, peer-reviewed evidence

Outcomes from two PositiveLinks pilots were published across four peer-reviewed papers. The results demonstrated that a well-designed mobile platform could move clinical outcomes in a population that the healthcare system had failed to retain.

+119%
Retention in Care — Visit Constancy
Visit constancy rose from 26% at baseline to 57% at 12 months. HRSA-1 retention compliance improved from 48% to 80% (+67%) over the same period.
Dillingham et al., AIDS Patient Care and STDs, 2018
+64%
Viral Suppression
Viral suppression rose from 47% at baseline to 77% at 12 months — approaching the national target of 80%, from a population starting well below it.
Dillingham et al., AIDS Patient Care and STDs, 2018
−7%
HIV Stigma Reduction (Men)
Stigma scores measured by the validated Berger HIV Stigma Scale dropped 7% among men and 4% across all participants at 12 months — a meaningful shift in a psychological barrier to care engagement.
Flickinger, DeBolt et al., AIDS and Behavior, 2018
LifeLong Medical Care (FQHC)
Care We Trust: Homeless & HIV+ · Oakland, CA · 2020
Real-World Deployment

Clinical Outcomes (6 Months)

Viral Suppression 78%
Retention in Care 100%
ED Visits −83%
Hospital Stays −75%
Medical Case Management +175%
Medi-Cal Wrap Revenue +$286.74/mo
ROI on $67/patient cost 327%

Population Profile

Avg. Diagnoses per Patient 9.3
Substance Use Diagnoses 78%
Mental Health Diagnoses 67%
Avg. Years Since HIV Dx 9.4
100%
Reported CAREiSCOPE helps them take their medications regularly
96%
Would recommend CAREiSCOPE to people they know
90%
Felt more engaged with their healthcare team through the platform

Built to operate in real clinical environments

CAREiSCOPE was designed from the infrastructure layer up for clinical deployment — not retrofitted for HIPAA compliance after the fact. Every system component was architected around the assumption that it would handle protected health information for the most vulnerable patient populations.

The three-tier architecture — member app, HIPAA-compliant secure cloud, and clinical administrative console — allowed bidirectional data flow between patients and care teams, while maintaining strict access controls and audit logging throughout.

The admin console exposed an API layer for EMR and HIT integration, enabling CAREiSCOPE to function as a connective tissue layer between patient-facing engagement and institutional clinical systems — rather than a standalone silo.

Patient Applications iOS · Android
Infrastructure HIPAA-Compliant Secure Cloud
Admin Console Web + iOS · 24/7 Access
Integration Layer API for EMR & HIT Systems
Localization Real-Time · 100+ Languages
Video Visits Telemedicine · HRSA-Compliant
Member Layer
Patient-Facing Mobile App
Invitation-only iOS/Android experience handling medication queries, mood and stress monitoring, peer community, secure messaging, appointment tracking, labs monitoring, and HIPAA-compliant document submission.
Infrastructure Layer
HIPAA-Compliant Secure Cloud
Central data layer with bidirectional PHI flow, audit logging, access controls, and secure storage. Designed for real-world clinical deployment, not pilot conditions — with 24/7 uptime requirements.
Clinical Layer
Administrative Console & Analytics
Web-based portal with member dashboards, predictive alerting, dynamic reporting, content management, video visits, remote monitoring, and user management. API-enabled for EMR integration.
Engagement Layer
RealHealthRewards Incentive Program
Data plan reimbursement program tied to engagement thresholds — bundled with CAREiSCOPE Premium. Managed carrier partnerships with Boost, Cricket, Assurance, MetroPCS, and T-Mobile.
Had I had this app when I was newly diagnosed, I believe wholeheartedly that I would not have struggled as much. It is very important to know that someone cares. I can be in constant contact with my whole team.
Kim W. Poet, Advocate, Mother & Program Member

Key Insights

Design Principle

Constrain for the most marginalised user

The decisions we made for the most vulnerable patients — low literacy, no reliable data, high stigma — produced a more robust, more usable product for everyone. Designing for the median user produces median outcomes.

System Design

Behavioral economics belongs in the architecture

The incentive loop wasn't a marketing feature — it was a systems design decision that solved a social determinants problem. When behavioral theory is embedded in the product architecture, not layered on top of it, the outcomes follow.

Research to Product

Evidence is a competitive moat

Most digital health products lack clinical evidence for what they claim to do. Having peer-reviewed outcomes data changed every conversation — with funders, with health systems, with regulators. The research investment was a product asset.